Diagnostic Utility of Serum Testosterone in Prostate Cancer

Abstract

Abstract

strong This study investigated the relationship between serum testosterone levels and prostate cancer diagnosis. Serum testosterone levels were measured in 40 prostate cancer patients, confirmed by biopsy and PSA testing, and 40 age-matched controls randomly selected from the general population. Testosterone levels were determined using a Human ELISA kit (Fisher Company, Catalog Number: FC-TESTO-08). The results indicated that 75% (30/40) of prostate cancer cases exhibited testosterone levels below the normal range (3.5–8.6 ng/ml), 15% (6/40) had levels above the normal range, and 10% (4/40) were within the normal range. The mean testosterone level in prostate cancer cases (2.77 ± 4.18 ng/ml) was significantly lower than in controls (6.90 ± 3.31 ng/ml) (p < 0.001). These findings suggest a correlation between low testosterone levels and prostate cancer.