Rate of Acute Complications of Blood and Blood Products Transfusion among Children at Jafar Ibn Ouf Hospital, Khartoum, Sudan,2022

Abstract

 Blood transfusion is the process of transferring blood or blood products into 
one`s circulation intravenously. transfusions are used for various medical conditions to replace 
lost components of the blood. early transfusions used whole blood, but modern medical 
practice commonly uses only components of the blood, such as red blood cells, white blood 
cells, plasma, clotting factors, and platelets. Objectives: To assess the Rate of Acute 
Complications of Blood and Blood products Transfusion among Children at Jaffar Ibn Ouf 
Hospital, Khartoum, Sudan,2021. Methodology: It was a cross-sectional, Observational, 
descriptive hospital-based study. Data were collected using a checklist including brief clinical 
history and examination and laboratory investigation, type of blood transfusion, and short-term 
complications. Data were cleaned and entered into a Microsoft Excel data sheet and were 
analyzed using SPSS latest version software. Result: A total of 130 pediatric patients 
participated in this study their ages ranged from 1-17 years, most of them; 56 (43.1%) were 
aged less than 5 years. Of most patients, 89 (68.5%) had blood transfusions based on both 
clinical conditions and lab results, and 24 (18.5%) patients had blood transfusions based on 
their clinical conditions. In most patients, 124 (95.4%) had a complete transfusion. Only 15 
(11.5%) patients developed blood reactions among them 8 (53.3%) patients developed febrile 
non-hemolytic transfusion reaction, 6 (40%) patients developed an allergic reaction, and 1 
(6.7%) patient developed transfusion-related acute lung injury. According to patients’ 
outcomes; most of them 123 (94.6%) were discharged, and 2 (1.5%) cases of death. 
Conclusion: The main limitation of this study was that it was conducted in only one hospital,
and the results may differ in other hospitals. Although our hospital serves a large geographical 
catchment area with numerous referrals, we do not know if current data accurately reflect the 
overall transfusion pattern in other similar health facilities or the country as a whole due to a 
lack of local comparable data. A multicenter survey is advised because it can provide more data 
and more solid conclusions.